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Modernising Medical Careers (MMC) in the UK—a debacle—are the royal colleges at fault?Attempts to modernise postgraduate medical training in the
United Kingdom have been a spectacular failure. In particular the activities of
the Medical Training Application Service (MTAS) resulted in mass demonstrations
by junior doctors. Justifiably it seems because of the failure of a computerised
system to process job applications of some 30,000 for 22,000 positions.
A spin-off for us is an influx of UK graduates to bolster
our ailing hospital staffing situation. However, as reported in the
BMJ, some believe that both the British Medical Association (BMA) and
the royal colleges let the young doctors down.
In particular “the question the royal colleges have to
answer is how and why they became complicit in a system for postgraduate
education that meant they had no influence on MTAS until it was too late.”
The chairman of BMA resigned over the issue.
BMJ 2007;334:724
Aspirin dose for the prevention of cardiovascular disease—low dose is bestPlacebo-controlled trials to confirm the benefit of aspirin
in the treatment and prevention of atherosclerotic disease complications have
used dosages ranging from 50 mg to 1300 mg/d. So what is the best dose and why
is it best?
The authors of this paper did a systematic review of the
English-language literature on this topic and have come up with an unequivocal
recommendation that dosages greater than 75 to 81 mg/d do not enhance efficacy,
whereas larger doses are associated with an increased incidence of bleeding
events, primarily related to gastrointestinal tract toxicity.
I think that we could settle for 100 mg daily in New
Zealand.
JAMA
2007;297:2018–24
Antiplatelet agents for prevention of pre-eclampsia—more good news about low-dose aspirinPre-eclampsia is a multisystem disorder of pregnancy that is
usually associated with hypertension and proteinuria and may lead to risks for
the baby including poor intrauterine growth and premature birth. The cause of
pre-eclampsia remains unclear but antiplatelet agents (particularly low-dose
aspirin) may prevent or delay it.
This meta-analysis of 31 randomised trials confirms that
antiplatelet agents during pregnancy are associated with moderate but consistent
reductions in the relative risk of pre-eclampsia, of birth before 34
weeks’ gestation, and of having a pregnancy with a serious adverse
outcome.
Lancet
2007;369:1791–8
Tonsillectomy and adenoidectomyIn the not too distant past these operations were regarded
as routine for the under 5 year old. Tonsillectomy is no longer so popular but
what about adenoidectomy?
In this review article, the authors examine the evidence and
conclude that adenoidectomy alone improves nasal airflow and the sense of smell
and taste. Growth after adenoidectomy may in part be due to an improved appetite
associated with the improvement in smell and taste.
And as part of the surgical management of glue ear where
watchful waiting has failed and the child is over three years of age,
adenoidectomy with grommet surgery appears to be more effective than
adenoidectomy alone.
Finally, adenoidectomy appears to be effective as part of
the management of childhood sleep apnoea syndrome, when combined with
tonsillectomy, although high-level evidence of efficacy is lacking.
The Journal of Laryngology
and Otology 2007;121:209–14
Human pheromone responses—sex and the noseIn this very interesting paper it is pointed out that the
olfactory neurones and the limbic system are phylogenetically very
‘old’ part of the mammalian brain that governs emotions and
behaviours, such as aggression, fear or mating responses.
Pheromones, being chemical messengers related to
reproduction, are sensed by olfaction, hence the nose is or could be a sexual
organ. Apparently young babies can identify, and are attracted to, both the
axillary and the breast odours of their own mother but not of other mothers, and
that this is not based upon memory of that odour. Mothers too can recognise the
odour or their own baby.
Furthermore, several studies have shown that women are far
better at odour detection than men. It is biologically more important for a
woman to choose the correct mate than a man, as women have a much larger
parental investment; their better sense of smell may reflect this.
So, what about perfumes, deodorants, and after-shave?
J R Soc Med
2007;100:268–74
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