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Psychotropic medications for elders in residential
care
Matthew Croucher
Concern about how psychotropic medicines are being
prescribed for elders living in residential care is bubbling away in the New
Zealand community, in international political and regulatory arenas, and in the
scientific literature. This is mainly driven by a keener appreciation of various
serious adverse drug reactions that may accrue to elders treated with such
medications; the limited efficacy of some of these agents for several common
problems such as “sundowning”; rising costs associated with using
expensive medicines; and a sense that ‘there must be a better
way’.
There is a group of people I come into contact with
regularly whose management is often very challenging, as it will be for many
readers. Following a sundowning pattern, agitation and even frank aggression
become more common as the afternoon wears on. Intrusive care-eliciting behaviour
increases at exactly the time that the carers need to absent themselves to
deliver the evening meal and engage in staff handover.
It is very tempting to prescribe a touch of medication to
ameliorate this syndrome as it is genuinely distressing to all concerned.
Demented elderly in resthome care? No: my own children (whom I hasten to add
have never been exposed to haloperidol). Why do we sanction medication for the
former but recoil from using drugs for the latter?
Whether or not there is a ‘better way’, the
residential care sector in which this prescribing is occurring faces very
significant challenges over the next 30 years. Indeed, the current general
practice, nursing, and allied health professional workforce engaged in caring
for elders who live in care facilities is already stretched—with many
shortfalls and marked inequity around the country. The same is true in relevant
secondary care settings. This inevitably means that skill levels are not optimal
and that staff turnover is high.
The workforce is itself ageing, especially in primary care
medicine and nursing, with no compensatory peak in recruitment into these areas
of practice. Across all professional groups, there is (on average) less glamour,
lower remuneration, and poorer career advancement opportunities associated with
this sector compared with others.
At the same time, the well-known twin impact of the ageing
baby-boomers and marked increases in the longevity of current cohorts of elders
mean that the population of people in the country who might benefit from or
require residential care is growing rapidly. This immediate and dramatic
increase in the number of New Zealanders over 85 years old is still largely
ignored by the media and, one suspects, health planners whose attention is
somewhat nervously focussed on the baby-boomers.
We also know that elders in care have a high prevalence of
the common psychiatric disorders such as depression, anxiety, psychosis,
delirium, and dementia. Despite the swing in emphasis in modern best-practice
from medicalised and pharmacological management to more conservative
psychosocial intervention plus medication as an adjunct, it is perhaps not
surprising that a great deal of medicine is still prescribed given the context
as I have described it. Indeed, it would not be surprising if there were a trend
for prescribing to increase.
This issue’s study by Tucker and
Hosford1 is an important contribution to
thinking about the pharmacological aspects of the challenge of providing
excellent residential care because there are no other published surveys of
psychotropic utilisation in this setting in New Zealand.
A particular strength is that the survey has been repeated
over a 15-year period. The main messages are a mixed bag of the potentially
encouraging and the probably worrying. It may be a good thing that
antidepressant prescribing has increased dramatically, although one worries
about overcalling depression, a lack of more human, problem-focussed
interventions for low mood, and the possibility that medications get started and
never stopped.
It is good news that antipsychotic prescribing has remained
stable and that doses are generally not large, but the mean doses of quetiapine
and olanzapine in particular were still fairly high (which poor souls are
getting much more than average?) and the marked shift from typicals to atyipcals
cannot be supported by evidence in terms of efficacy, although the risk of
extra-pyramidal side effects is generally lower.
The reduced regular usage of potent shorter-acting
benzodiazepines is heartening, but on the other hand, do we really need to
prescribe such a high proportion of long-acting agents instead? And what of
psychotropic polypharmacy, its monitoring, and its reduction?
The main message from this paper that leaps out for me is
that rates of psychotropic prescribing varied greatly between facilities
offering more or less the same level of care. What can this mean from such a
good regional sample other than that prescriber and environment factors are very
potent influences upon prescribing patterns? Perhaps this means that educative
and care-resource interventions can be selectively applied to reduce medication
usage for outliers; perhaps it predicts a failure of applied logic to shift
these variations in practice.
Of all these medicines, concern is highest for the
antipsychotic drugs—necessary and demonstrably effective in the right
setting at the right dose with the right support, but toxic in the wrong
setting.
PHARMAC has recently commissioned the country’s old
age psychiatrists to write guidelines for the prescription of these agents in
residential care and a Primary Care group has been tasked with producing an
educative and audit package. These endeavours must be applauded.
But they are not enough. The fundamental problem is not
over-prescription of any particular class of drugs—it is an urgent need to
improve our somewhat patchy and imperfect care for these most vulnerable
citizens in the face of the great challenges that they present to carers, all at
a time when the clinical need : clinical resources ratio is beginning to
increase exponentially.
Disclaimer: The opinions expressed in
this editorial are the author’s own and do not necessarily reflect the
views of the any of the organisations with which he is associated, nor the
NZMA.
Competing interests: No relevant
financial interests. Convenor of FPOA(NZ) / PHARMAC Antipsychotic Prescribing
Guidelines Project.
Author information: Matthew Croucher,
Acting Chair, New Zealand Branch, Faculty of Psychiatry of Old Age of the Royal
Australian and New Zealand College of Psychiatrists; Consultant Psychiatrist of
Old Age, Canterbury District Health Board; Senior Clinical Lecturer, University
of Otago, Christchurch
Correspondence: Dr Matthew Croucher, The
Walshe Centre, PO Box 4345, Christchurch, New Zealand. Fax: +64 (0)3 3770267;
email: matthew.croucher@cdhb.govt.nz
Reference:
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