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The New Zealand Medical Journal

 Journal of the New Zealand Medical Association, 12-December-2008, Vol 121 No 1287

Splenic infarction secondary to subacute infective endocarditis
Amer A Alkhatib, Fateh A Elkhatib
A 32-year-old man with Glanzmann’s thromboasthenia presented with a 5-week history of bleeding gums and a 3-week history of left upper quadrant abdominal pain. His vital signs were normal. Physical examination was significant for a holosystolic murmur consistent with mitral regurgitation, and for a tender abdomen at the left upper quadrant.
Laboratory values were: WBC 14,600 cells/mm3, neutrophils 84%, and ESR 98 mm/hr. A contrast CT of the abdomen showed a wedge-shaped hypodense splenic lesion, consistent with splenic infarct (Figure 1 and Figure 2).
Figures 1 and 2 showing wedge-shaped hypodense lesion in the spleen
What is the diagnosis?
Author information: Amer A Alkhatib, Adjunct Clinical Assistant Professor, Department of Pharmacotherapy, Washington State University, Spokane, Washington, USA; Fateh Ahmad Elkhatib, Hospitalist, Department of Internal Medicine, Holy Family Hospital, Spokane, Washington, USA
Correspondence: Dr Amer A Alkhatib, Department of Pharmacotherapy, Washington State University, PO Box 1495, Spokane, Washington 99210, USA. Email: khatibamer@yahoo.com
References:
  1. Gorg C, Seifart U, Gorg K. Acute, complete splenic infarction in cancer patient is associated with a fatal outcome. Abdominal Imaging. 2004 Mar-Apr;29(2):224–7.
  2. Baddour LM, Wilson WR, Bayer AS, et al. Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America. Circulation. 2005 Jun 14;111(23):e394–434.
     
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