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New Zealand pertussis epidemiology and the Global
Pertussis Initiative immunisation strategies
In July 2010 a Strategy Workshop was convened to review New
Zealand pertussis epidemiology and the Global Pertussis Initiative immunisation
strategies. The meeting was co-chaired by the Ministry of Health with
GlaxoSmithKline (GSK) providing the venue and some travel support.
Attendees included delegates from district health boards
(DHBs), Environmental Science and Research (ESR), RNZCGP and the Ministry of
Health’s Immunisation Technical Forum.
It has become increasingly clear that achieving high
childhood immunisation coverage alone does not completely protect infants from
pertussis. Both natural and vaccine derived immunity are not lifelong, lasting
only a few years. This means that older siblings, adult household members and
other adults, such as grandparents, with a cough illness can be a source of
infection for those too young to have completed primary
immunisation.1,2 At least 8% of adults with a
cough illness of more than 7 days duration are likely to have
pertussis.3 The source of infection of infants
hospitalised with pertussis, when it can be identified, is usually an older
household member, most commonly the
mother.4
The Global Pertussis Initiative (GPI) addressed how best to
control pertussis and described seven key strategies to improve pertussis
control. These are:
New Zealand already has the three routine
childhood vaccination strategies recommended by the GPI, namely an infant
immunisation programme, a four year old childhood booster dose and an adolescent
dose. Coverage for the infant schedule in New Zealand is increasing and now 90%,
though only approximately one-half of children receive their immunisations on
time, within four weeks.
Data on the coverage of the 4-year and 11-year booster doses
are lacking. The recent epidemiology suggests that improved vaccination coverage
has had an impact on the incidence of pertussis with the current epidemic not
reaching the heights of prior epidemics.
Following presentations to set the scene and detailed
discussion the key recommendations of the forum were to improve delivery of the
current immunisation programme ensuring that 95% if infants received 3 doses of
a pertussis containing vaccine by 6 months of age, to fund DHBs to offer
pertussis immunisation to healthcare workers.
In particular, those who work with neonates and young
children should receive a pertussis containing vaccine every 10 years and to
pilot the promotion of cocoon immunisation around newborns. This would involve
ensuring that, on diagnosis of pregnancy, all other children in the household
are up-to-date with their immunisation schedules, immunising all mothers after
birth unless a dose of a pertussis containing vaccine has been received within
the last 10 years and providing information to new parents to encourage
grandparents and other household and regular contacts to be immunised.
Universal adult immunisation and immunisation of childcare
workers were not supported, at present, by the forum.
These recommendations, with greater supporting detail, have
been forwarded to the Ministry of Health for consideration. A full report is
available from Dr Stewart Reid at the email address below.
Stewart Reid
General Practitioner Ropata Medical Centre, Lower Hutt and Senior Lecturer, Department of Population Health, University of Auckland stewart_christine@mac.com Elizabeth Wilson
Paediatric Infectious Diseases Specialist Starship Children's Hospital, Auckland District Health Board. References:
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