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Anterior cruciate ligament reconstructions, the
debate continues—with another response by Assoc Prof Hooper
In 2005 the Cochrane Collaboration analysed all randomised
and quasi-randomised trials comparing surgery with conservative treatment of ACL
rupture in adult.1 They concluded that there
was no evidence to determine whether current surgical techniques or conservative
management was best treatment for ACL injuries. They recommended that good
quality randomised trials were required to remedy this situation. In 2009 this
paper was updated with no changes to its conclusions.
In his reply to my previous letter Mr Hooper promotes ACL
reconstruction, claiming it "improves knee function in greater than 90%, with
the majority of patients returning to aggressive sporting and working
activities, especially those activities that involve twisting or rapid change of
direction." Neither of the papers he quotes support his opinion. The first paper
is a non-randomised retrospective study promoting ACL reconstruction in the
non-athlete.2 The second paper is an assessment
of 70 randomised controlled trials in regard to surgical technique and
rehabilitation of ACL injuries.3 The authors
concluded that none of the papers were high quality and they stressed the need
for further studies.
I found five papers on the natural history of an ACL
rupture. The most rigorous of these studies involved 50 patients with complete
ACL ruptures.4 The MRI findings were that 21
(42%) had a normal ACL and 20 (40%) had a partial repair at 3 months. Mr Hooper
claims that full thickness midsubstance tears (of the ACL) rarely heal. He is
wrong. Nor do the papers he cite support his opinion. The first paper explores
the effect of anterior cruciate ligament trauma and bracing on knee
proprioception.5 The other follows 49 patients
who had ongoing problems with their knees following ACL
ruptures.6
Mr Hooper justifies ACL reconstruction by stating there is
no evidence that it is responsible for the development of long-term
osteoarthritis. He misses the point of my letter. The onus is on the surgeon to
prove that ACL reconstruction doesn't cause long-term osteoarthritis and that
study hasn’t been done. He also states "Instability is the commonest
indication for ACL reconstruction" without supporting evidence. In my clinical
experience instability has never been the indication for an ACL repair, but
rather the patient has an ill-defined fear of future problems with the joint if
they don't have surgery.
Mr Hooper claims my concerns regarding ACL reconstructions
are inappropriate and misinformed. How so? The papers he cites to support his
opinion are irrelevant to his claims. His “Best Practice” is based
on an ACC document written in 2002 that has been superseded twice by the
Cochrane Collaboration.
ACL reconstruction surgery has no randomised controlled
trial (RCT) support.
Dr Nicholas Cooper
General Practitioner Epsom, Auckland References:
Assoc Prof Hooper’s response
The anterior cruciate ligament (ACL) is not a redundant
structure. Rupture causes anterolateral rotary instability which can be
disabling, even in routine activities of daily living. Some patients can cope
with life changes to accommodate for this but most continue to experience
episodes of instability. The overwhelming literature and clinical experience
supports reconstruction in these patients to improve knee stability.
ACL reconstruction became popular in the late 1970s when the
instability pattern was recognised and procedures that produced less morbidity
were advanced. This was popularised because ACL ruptures rarely healed. Today
the treatment of ACL rupture is being directed towards methods of manipulating
the environment to enable ACL healing. The millions of dollars directed towards
the genetic engineering to achieve this tissue modification would not be spent
if the ACL healed.
Constructing a RCT at this stage in the evolution of ACL
treatment would be impossible. Firstly, gaining ethical approval would be
unlikely and secondly, recruitment into the non-operative group in a young
active cohort would be difficult at best.
It is true that there are few RCTs to support reconstruction
but this is not uncommon in surgical practise where a procedure has produced
such a profound improvement in function. Few would disagree that total hip
replacement has been a successful operation but there have never been any RCTs
to prove this.
Does this mean that hip replacement is not a proven
procedure?
Assoc Professor Gary Hooper
Head of Department, Orthopaedic Surgery and Musculoskeletal Medicine University of Otago, Christchurch |
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