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This Issue in the Journal
Great expectations: use of molecular tests and
computerised prognostic tools in New Zealand cancer care
Deborah M Wright, Rob McNeill, Arend E H Merrie, Cristin G Print There is an international drive to improve the survival of
patients with cancer by tailoring treatment more precisely to the
individual’s tumour; ‘personalised medicine’. Personalised
medicine may include consideration of important clinical and pathological
factors, e.g. tumour stage, and, increasingly, consideration of the molecular
characteristics of individual tumours. We surveyed New Zealand cancer clinicians
and discovered that molecular tests and computerised prognostic tools are used
by many clinicians and influence the treatment provided to cancer patients. In
addition we found that most clinicians predict that the impact and influence of
these technologies will increase over the next 10 years. This has important
clinical and economic implications for New Zealand’s cancer control
strategy.
Clinical trials in New Zealand—an
update
Vickie Currie, Andrew Jull An average of 180 clinical trials per year were conducted
2005–2009, up from an average of 111 per year in 1998–2003. Early
phase trials accounted for much of the increase, probably because of an increase
in the number of early phase units in New Zealand. Most commercial trials were
compliant with the Committee of Medical Journal Editors (ICMJE) requirement to
register trials, but non-commercial trials were not so compliant.
Short and long term outcomes of oesophagectomy in a
provincial New Zealand hospital
Fadhel Al-Herz, David Healey, Tarik Sammour, Josese Turagava, Bruce Rhind, Mike Young Oesophagectomy (resection of the oesophagus) is a very
complex surgical procedure associated with a significant morbidity and mortality
rate. There is very little published data from New Zealand, with no published
data from a non-Tertiary New Zealand hospital. Data from 68 patients who
underwent oesophagectomy at Palmerston North Hospital were analysed. Survival
outcomes of oesophageal resection in this provincial New Zealand hospital were
comparable to published series from national and international tertiary
centres.
Arcobacter species in diarrhoeal faeces
from humans in New Zealand
Owen Mandisodza, Elizabeth Burrows, Mary Nulsen Arcobacter species used to be classified as
campylobacters but differ in a number of properties. Overseas studies have shown
that arcobacters can be found in healthy, and occasionally, sick animals as well
as in poultry and other meats, shell fish, seawater, fresh water and the
environment. Our study found two Arcobacter species, A. butzleri
and A. cryaerophilus, in 0.9% of 1380 patients with diarrhoea from
the Hawke’s Bay region of New Zealand. A number of these patients had
persistent or watery diarrhoea but one-third were also infected with another
enteric pathogen. Arcobacters are considered emerging enteric pathogens but
further studies would be valuable in determining their overall importance in
disease of humans.
Is late-night salivary cortisol a better screening
test for possible cortisol excess than standard screening tests in obese
patients with Type 2 diabetes?
Elna Ellis, Paul K L Chin, Penelope J Hunt, Helen Lunt, John G Lewis, Steven G Soule One of the rare causes of diabetes mellitus and obesity is
having excessive production of cortisol, a steroid hormone. There are two
routine tests available to check patients for excess cortisol, including: a 24
hour urine collection; or a blood test. A newer test involves checking for
cortisol levels in saliva, which is potentially a more convenient test. Our
study showed that the salivary cortisol test was inferior to the other two
tests, and the urine collection test was the best.
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