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| Journal of the New Zealand Medical Association, 03-April-2009, Vol 122 No 1292 |
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[full text] [PDF] Successful treatment of transplant-associated microangiopathy with rituximab
Helen Marr, Emma-Jane McDonald, Eileen Merriman, Mark Smith, Hilda Mangos, Catherine Stoddart, Peter Ganly
AbstractThe microangiopathic anaemia with thrombocytopenia—which can occur after haematopoietic stem cell transplant—resembles thrombotic thrombocytopenic purpura but has different pathophysiology and does not respond to plasma exchange. We describe a patient with severe manifestations of this disorder who recovered promptly following treatment with rituximab, an anti-CD20 antibody.
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